| Data Request ID | Lead Investigator | Institution | Research Proposal Title | Public Disclosure | Data Contributor(s) | Altmetric Score | PubMed Citation Total |
|---|---|---|---|---|---|---|---|
| 3288 | Marc-Antoine Sparfel | Tours Hospital | MIDRA: influence of demographic and environmental factors on anti-tumor necrosis factor efficacy in rheumatoid arthritis a systematic review and meta-analysis of randomized controlled trials | Law-Wan J, Sparfel M, Derolez S, et al. Predictors of response to TNF inhibitors in rheumatoid arthritis: an individual patient data pooled analysis of randomised controlled trials. RMD Open 2021;7:e001882. doi: 10.1136/rmdopen-2021-001882 | AbbVie, Pfizer, UCB | 7 | |
| 3320 | John Frew | Rockefeller University | Analysis of Outcome Measures in Hidradenitis Suppurativa | Frew, J. W., Singh, N., Jiang, C. S., Vaughan, R., & Krueger, J. G. (2021). The Impact of Body Mass Index Upon the Efficacy of Adalimumab in Hidradenitis Suppurativa. Frontiers in Medicine. doi: 10.3389/fmed.2021.603281 | AbbVie | 5 | |
| 3762 | Lin Wang | Johns Hopkins School of Public Health, Johns Hopkins Hospital | The relative efficacy and safety of apalutamide, enzalutamide, abiraterone, and darolutamide for nonmetastatic castration-resistant prostate cancer | Lin Wang, MD, PhD, Channing Paller, MD, Hwanhee Hong, PhD, Lori Rosman, MLS, Anthony De Felice, MHS, Otis Brawley, MD, G Caleb Alexander, MD, MS, Comparison of Treatments for Nonmetastatic Castration-Resistant Prostate Cancer: Matching-Adjusted Indirect Comparison and Network Meta-Analysis, JNCI: Journal of the National Cancer Institute, 2021;, djab071, doi: 10.1093/jnci/djab071 | Pfizer, Project Data Sphere | 10 | |
| 4036 | Akira Kimata | University of Tsukuba | Optimal interruption time of dabigatran per OS to Ablation (O-A time) in patients with atrial fibrillation Integrated analysis of 2 randomized controlled clinical trials | Akira Kimata, Akihiko Nogami, Hiro Yamasaki, Tomohiro Ohigashi, Masahiko Gosho, Miyako Igarashi, Yukio Sekiguchi, Masaki Ieda, Hugh Calkins, Kazutaka Aonuma, Optimal interruption time of dabigatran oral administration to ablation (O-A time) in patients with atrial fibrillation: Integrated analysis of 2 randomized controlled clinical trials, Journal of Cardiology, 2021, ISSN 0914-5087, doi: 10.1016/j.jjcc.2020.12.010 | Boehringer Ingelheim | 2 | |
| 4043 | Janneke van der Woude | Erasmus Medical Center | Effect of treatment on lipid profiles in patients with inflammatory bowel disease a systematic review and meta-analysis | J A M Sleutjes, J E Roeters van Lennep, E Boersma, A C de Vries, C J van der Woude, P292 Effect of drug therapy on the lipid profiles of patient with Inflammatory Bowel Disease: a systematic review and meta-analysis, Journal of Crohn's and Colitis, Volume 15, Issue Supplement_1, May 2021, Pages S322–S323. doi: 10.1093/ecco-jcc/jjab076.416 | Pfizer | N/A | |
| 4043 | Janneke van der Woude | Erasmus Medical Center | Effect of treatment on lipid profiles in patients with inflammatory bowel disease a systematic review and meta-analysis | Sleutjes, JAM, Roeters van Lennep, JE, Boersma, E, et al. Systematic review with meta-analysis: effect of inflammatory bowel disease therapy on lipid levels. Aliment Pharmacol Ther. 2021; 00: 1– 14. doi: 10.1111/apt.16580 | Pfizer | 10 | |
| 4316 | Martin Okun | Fort Healthcare | Geospatial and Seasonal Variation in Psoriasis Severity Analysis of Placebo Response Data from Phase 3 placebo-controlled trials in moderate-severe psoriasis. | 268 Analysis of association between variation in ambient solar ultraviolet exposure and disease severity for patients with moderate-severe psoriasis Okun, T.S. et al. Journal of Investigative Dermatology, Volume 141, Issue 5, S48 doi: 10.1016/j.jid.2021.02.290 | AbbVie | 0 | N/A |
| 4330 | Laure Gossec | Sorbonne Université | Domains of health important for Rheumatoid Arthritis patients can be assessed separately: Reliability and Responsiveness of the Rheumatoid Arthritis Impact of Disease Score - 7 items (RAID.7i) | Duarte C, Santos EJF, Ferreira RJO, et al. Validity and reliability of the EULAR instrument RAID.7 as a tool to assess individual domains of impact of disease in rheumatoid arthritis: a cross-sectional study of 671 patients RMD Open 2021;7:e001539. doi: 10.1136/rmdopen-2020-001539 | Pfizer | 8 | |
| 4918 | Nina Hilkens | Radboudumc Nijmegen | Association between blood pressure, blood pressure variability and the risk of post-stroke dementia | Hilkens, Nina A.; Klijn, Catharina J.M.; Richard, Edo Blood pressure, blood pressure variability and the risk of poststroke dementia, Journal of Hypertension: March 11, 2021 - Volume Publish Ahead of Print - Issue doi: 10.1097/HJH.0000000000002841 | Boehringer Ingelheim | 0 | 4 |
| 5073 | Philip Robinson | University of Queensland | Assessment of treatment outcome using ASAS40 with etanercept in non-radiographic axSpA by baseline CRP - a re-analysis of trial data | Tam, H.K.J., Nash, P. and Robinson, P.C. (2021), The Effect of Etanercept in Nonradiographic Axial Spondyloarthritis by Stratified C-Reactive Protein Levels. ACR Open Rheumatology. doi: 10.1002/acr2.11312 | Pfizer | 2 | |
| 5074 | Sebastian Zundler | University Hospital Erlangen | Evaluation of the relationship between vedolizumab peripheral blood serum level at week 6 and binary clinical outcomes at week 10/14 - a meta-analysis | Becker E, Dedden M, Gall C, et al. Residual homing of ?4?7-expressing ?1+PI16+ regulatory T cells with potent suppressive activity correlates with exposure-efficacy of vedolizumab. Gut Published Online First: 30 August 2021. doi: 10.1136/gutjnl-2021-324868 | Takeda | 17 | |
| 5086 | Junko Takeshita | University of Pennsylvania | A Systematic Review to Describe the Demographic Diversity of Dermatologic Clinical Trial Participants for Common Dermatologic Diseases | 560 Racial/ethnic diversity in U.S. clinical trials for acne, atopic dermatitis, and psoriasis Sevagamoorthy, A. et al. Journal of Investigative Dermatology, Volume 141, Issue 5, S97 doi: 10.1016/j.jid.2021.02.587 | AbbVie, Lilly, Regeneron | N/A | N/A |
| 5095 | Mathilde Nijkeuter | University Medical Center Utrecht | Assessing bleeding risk in patients with cancer-associated thrombosis | de Winter MA, Dorresteijn JAN, Ageno W, Ay C, Beyer Westendorf J, Coppens M, Klok FA, Moustafa F, Riva N, C Ruiz Artacho P, Vanassche T, Nijkeuter M. Estimating Bleeding Risk in Patients with Cancer-associated Thrombosis: External Validation of Existing Risk Scores and Development of a New Risk Score [abstract]. Res Pract Thromb Haemost. 2021; 5 (Suppl 1). https://abstracts.isth.org/abstract/estimating-bleeding-risk-in-patients-with-cancer-associated-thrombosis-external-validation-of-existing-risk-scores-and-development-of-a-new-risk-score/. Accessed July 23, 2021. | Daiichi Sankyo | N/A | |
| 5095 | Mathilde Nijkeuter | University Medical Center Utrecht | Assessing bleeding risk in patients with cancer-associated thrombosis | de Winter MA, Dorresteijn JAN, Ageno W, Ay C, Beyer-Westendorf J, Coppens M, Klok FA, Moustafa F, Riva N, Ruiz Artacho PC, Vanassche T, Nijkeuter M. Estimating Bleeding Risk in Patients with Cancer-Associated Thrombosis: Evaluation of Existing Risk Scores and Development of a New Risk Score. Thromb Haemost. 2021 Sep 20. doi: 10.1055/s-0041-1735251 | Daiichi Sankyo | 25 | |
| 5096 | Joo Sang Lee | Samsung Medical Center, South Korea | Harnessing genetic interactions to advance precision cancer medicine | Synthetic lethality-mediated precision oncology via the tumor transcriptome. Lee, Joo Sang et al. Cell, Volume 184, Issue 9, 2487 - 2502.e13. doi: 10.1016/j.cell.2021.03.030 | Tempus AI, Inc. | 69 | |
| 5098 | Christopher Baethge | University of Cologne Medical School | Dose-response relationships in antidepressant pharmacotherapy of depressive disorders with (S)SNRI: a systematic review and meta-analysis | Rink L, Adams A, Braun C, Bschor T, Kuhr K, Baethge C. Dose-Response Relationship in Selective Serotonin and Norepinephrine Reuptake Inhibitors in the Treatment of Major Depressive Disorder: A Meta-Analysis and Network Meta-Analysis of Randomized Controlled Trials. Psychother Psychosom 2021. doi: 10.1159/000520554 | Lilly | 7 | |
| 5163 | Susan Bates | Columbia University Medical Center | Assessing the tumor growth and decay rates in patients with pancreatic cancer treated with Gemcitabine/Abraxane: Comparing real world data with clinical trial data | Keith Sigel, Mengxi Zhou, Yeun-Hee Anna Park, Tinaye Mutetwa, Girish Nadkarni, Celine Yeh, Paz Polak, Carlie Sigel, Thierry Conroy, Béata Juzyna, Mark Ychou, Tito Fojo, Juan P Wisnivesky, Susan E. Bates, Gemcitabine plus nab-paclitaxel versus FOLFIRINOX for unresected pancreatic cancer: Comparative effectiveness and evaluation of tumor growth in veterans, Seminars in Oncology, 2021, ISSN 0093-7754. doi: 10.1053/j.seminoncol.2021.02.001 | Celgene Corporation | 4 | |
| 5165 | Byeongzu Ghang | Jeju National University Hospital | Reanalysis of CARES study to investigate the incidence of cardiovascular events and death after initiation and discontinuation of allopurinol and febuxostat | Ghang B, Lee JS, Kim J, Yoo B. Increased risk of cardiovascular events and death in the initial phase after discontinuation of febuxostat or allopurinol: Another story of the CARES trial. J Rheum Dis 2021; 28(1):219. Abstract | Takeda | N/A | N/A |
| 5166 | Thomas Metkus | Johns Hopkins University School of Medicine | Severe sepsis in the cardiac intensive care unit: management strategies and outcomes | Dugan, Eunice; Stephens, R. Scott; Schulman, Steven; Metkus, Thomas 1205: Sepsis in the Cardiac Intensive Care Unit: Demographics and Outcomes, Critical Care Medicine: January 2021 - Volume 49 - Issue 1 - p 605 doi: 10.1097/01.ccm.0000730708.28818.5e | Lilly | 0 | N/A |
| 5166 | Thomas Metkus | Johns Hopkins University School of Medicine | Severe sepsis in the cardiac intensive care unit: management strategies and outcomes | Feldman, E. W., Dugan, E., Stephens, R. S., Schulman, S., Zakaria, S., & Metkus, T. (2021). Presentation and outcomes of sepsis in the cardiac intensive care unit. American Heart Journal Plus: Cardiology Research and Practice, 7, 100040. doi: 10.1016/j.ahjo.2021.100040 | Lilly | 3 | |
| 5207 | Fasihul Khan | University of Nottingham | A systematic review and individual patient data meta-analysis of physiological biomarkers in idiopathic pulmonary fibrosis | Khan FA, Stewart I, Saini G, Robinson KA, Jenkins RG. A systematic review of blood biomarkers with individual participant data meta-analysis of matrix-metalloproteinase-7 in IPF. Eur Respir J. 2021 Sep 29:2101612. PMID: 34588192. doi: 10.1183/13993003.01612-2021 | BioLINCC, Boehringer Ingelheim, Johnson & Johnson, Roche | 23 | |
| 5207 | Fasihul Khan | University of Nottingham | A systematic review and individual patient data meta-analysis of physiological biomarkers in idiopathic pulmonary fibrosis | A systematic review and individual participant data meta-analysis of MMP-7 and outcomes in idiopathic pulmonary fibrosis. Fasihul Khan, Iain Stewart, Gauri Saini, Karen A Robinson, Gisli Jenkins. European Respiratory Journal Sep 2021, 58 (suppl 65) PA395; doi: 10.1183/13993003.congress-2021.PA395 | BioLINCC, Boehringer Ingelheim, Johnson & Johnson, Roche | 23 | |
| 5292 | Désirée van der Heijde | Leiden University Medical Center | Measurement properties of the instruments used in the outcome assessment of axial spondyloarthritis | Boel A, Navarro-Compán V, van der Heijde D. Test–retest reliability of outcome measures: data from three trials in radiographic and non-radiographic axial spondyloarthritis. RMD Open 2021;7:e001839. doi: 10.1136/rmdopen-2021-001839 | UCB | 1 | |
| 5352 | Elena Myasoedova | Mayo Clinic | Individualized Prediction of Treatment Response to Methotrexate in Patients with Rheumatoid Arthritis: A Machine Learning Approach | Duong S, Crowson C, Atkinson E, Athreya A, Davis J, Matteson E, Weinshilboum R, Wang L, Myasoedova E. Clinical Predictors of Response to Methotrexate in Patients with Rheumatoid Arthritis: A Machine Learning Approach Using Clinical Trial Data [abstract]. Arthritis Rheumatol. 2021; 73 (suppl 10). https://acrabstracts.org/abstract/clinical-predictors-of-response-to-methotrexate-in-patients-with-rheumatoid-arthritis-a-machine-learning-approach-using-clinical-trial-data/ | Roche, UCB | 27 | |
| 5456 | Terina Martinez | Critical Path Institute | Validation of a Model-based Clinical Trial Simulation Tool to Optimize Clinical Trial Design of Studies to Investigate Efficacy of Potential Therapies for Duchenne Muscular Dystrophy | Modeling informative drop out in a disease progression model of Duchenne Muscular Dystrophy. Rhoda Muse, Jane Larkindale, Sarah Kim, Stephan Schmidt, Juan Francisco Morales, Sudhir Sivakumaran, Ramona Belfiore-Oshan, Varun Aggarwal, Klaus Romero, Jackson Burton and Diane Corey. Statistics and PMx e.g. MBMA, Bayesian application/method, trial design, optimal design, machine learning, data mining. ACoP12 (2021) STPM-198 www.go-acop.org/?abstract=198 | CureDuchenne | N/A | N/A |
| 5456 | Terina Martinez | Critical Path Institute | Validation of a Model-based Clinical Trial Simulation Tool to Optimize Clinical Trial Design of Studies to Investigate Efficacy of Potential Therapies for Duchenne Muscular Dystrophy | Ramona Belfiore-Oshan, Varun Aggarwal, Rhoda Muse, Sarah Kim, Stephan Schmidt, Juan Francisco Morales, Karthik Linganeni, Sudhir Sivakumaran, Diane Corey, Klaus Romero, Terina Martinez. Acceleration of clinical trial design in Duchenne Muscular Dystrophy building a model-based Clinical Trial Simulation Tool. The Muscular Dystrophy Association (MDA) Clinical & Scientific conference, March 13-16, 2022 (Abstract). https://mdaconference.org/node/1556 | CureDuchenne | N/A | N/A |
| 5567 | Neeraj Narula | Hamilton Health Sciences | Impact of Ulcer Size and Extent of Inflammation On Ability To Achieve Endoscopic Healing In Crohn's Disease: An EXTEND Post-Hoc Analysis | Narula N, Wong ECL, Colombel J, et alPredicting endoscopic remission in Crohn’s disease by the modified multiplier SES-CD (MM-SES-CD) Gut Published Online First: 25 March 2021. doi: 10.1136/gutjnl-2020-323799 | AbbVie | 10 | |
| 5567 | Neeraj Narula | Hamilton Health Sciences | Impact of Ulcer Size and Extent of Inflammation On Ability To Achieve Endoscopic Healing In Crohn's Disease: An EXTEND Post-Hoc Analysis | Sa467 THE MODIFIED MULTIPLIER SES-CD (MM-SES-CD) PERFORMS BETTER THAN THE SES-CD FOR PREDICTION OF ENDOSCOPIC REMISSION IN CROHN'S DISEASE. Narula, Neeraj et al. Gastroenterology, Volume 160, Issue 6, S-509. doi: 10.1016/S0016-5085(21)01923-5 | AbbVie | N/A | |
| 7394, 5895, 6117 | Ashley Hopkins | Flinders University | Predictors of exposure, therapeutic and adverse effects of atezolizumab used in the treatment of advanced cancers | Hopkins AM, Kichenadasse G, Abuhelwa AY, McKinnon RA, Rowland A, Sorich MJ. Value of the Lung Immune Prognostic Index in Patients with Non-Small Cell Lung Cancer Initiating First-Line Atezolizumab Combination Therapy: Subgroup Analysis of the IMPOWER150 Trial. Cancers. 2021; 13(5):1176. doi: 10.3390/cancers13051176 | Roche | 16 | |
| 7394, 5895, 6117 | Ashley Hopkins | Flinders University | Predictors of exposure, therapeutic and adverse effects of atezolizumab used in the treatment of advanced cancers | Abuhelwa AY, Kichenadasse G, McKinnon RA, Rowland A, Hopkins AM, Sorich MJ. Machine Learning for Prediction of Survival Outcomes with Immune-Checkpoint Inhibitors in Urothelial Cancer. Cancers. 2021; 13(9):2001. doi: 10.3390/cancers13092001 | Roche | 17 | |
| 7394, 5895, 6117 | Ashley Hopkins | Flinders University | Predictors of exposure, therapeutic and adverse effects of atezolizumab used in the treatment of advanced cancers | Hopkins, A.M., Kichenadasse, G., McKinnon, R.A. et al. Efficacy of first-line atezolizumab combination therapy in patients with non-small cell lung cancer receiving proton pump inhibitors: post hoc analysis of IMpower150. Br J Cancer (2021). doi: 10.1038/s41416-021-01606-4 | Roche | 40 | |
| 7394, 5895, 6117 | Ashley Hopkins | Flinders University | Predictors of exposure, therapeutic and adverse effects of atezolizumab used in the treatment of advanced cancers | Hopkins, A. M., Abuhelwa, A. Y., McKinnon, R. A., Logan, J. M., Kichenadasse, G., Rowland, A., & Sorich, M. J. (2021). Smoking and immunotherapy efficacy in lung cancer by PDL1 subgroups: An individual participant data meta-analysis of atezolizumab clinical trials. European Journal of Cancer. doi: 10.1016/j.ejca.2021.10.020 | Roche | 2 | |
| 7394, 5895, 6117 | Ashley Hopkins | Flinders University | Predictors of exposure, therapeutic and adverse effects of atezolizumab used in the treatment of advanced cancers | Ahmad Y Abuhelwa, Joaquim Bellmunt, Ganessan Kichenadasse, Ross A McKinnon, Andrew Rowland, Michael J Sorich, Ashley M Hopkins. Enhanced Bellmunt risk score for survival prediction in urothelial carcinoma treated with immunotherapy. Clinical Genitourinary Cancer, 2021. doi: 10.1016/j.clgc.2021.11.010 | Roche | 15 | |
| 5925 | Min Hwan Kim | Yonsei University College of Medicine | Analysis of neutrophil to lymphocyte ratio (NLR) in ER+ breast cancer patients to predict palbociclib clinical response | On-treatment derived neutrophil-to-lymphocyte ratio and response to palbociclib and letrozole: Analysis of a multicenter retrospective cohort and the PALOMA-2 study. Chang Gon Kim, Min Hwan Kim, Jee Hung Kim, Seul-Gi Kim, Gun Min Kim, Tae Yeong Kim, Won-Ji Ryu, Jeeye Kim, Hyung Seok Park, Seho Park, Youngup Cho, Byeong-Woo Park, Seung Il Kim, Joon Jeong, and Joohyuk Sohn. Journal of Clinical Oncology 2021 39:15_suppl, 1066-1066. doi: 10.1200/JCO.2021.39.15_suppl.1066 | Pfizer | N/A | |
| 5931 | Youssef Zeidan | American University of Beirut Medical Center | Evaluation of Radiotherapy in Triple Negative Breast Cancer: Analysis of the BEATRICE trial | Kayali, M., Abi Jaoude, J., Mohammed, M. et al. Post-mastectomy Radiation Therapy in Triple-Negative Breast Cancer Patients: Analysis of the BEATRICE Trial. Ann Surg Oncol 29, 460–466 (2022). doi: 10.1245/s10434-021-10511-2 | Roche | 8 | |
| 5933, 5208 | Ahmad Abuhelwa | University of South Australia | Predictors of exposure, therapeutic and adverse effects of certolizumab pegol, baricitinib and tocilizumab used in the treatment of rheumatoid arthritis | Abuhelwa AY, Foster DJR, Manning-Bennett A, et al. Concomitant beta-blocker use is associated with a reduced rate of remission in patients with rheumatoid arthritis treated with disease-modifying anti-rheumatic drugs: a post hoc multicohort analysis. Therapeutic Advances in Musculoskeletal Disease. January 2021. doi: 10.1177/1759720X211009020 | Roche | 1 | |
| 5935 | Jian-Guo Zhou | The Second Affiliated Hospital of Zunyi Medical University | Longitudinal peripheral blood markers as dynamic predictors to identify efficacy and safety of patients treated with immune checkpoint inhibitors (ICIs) | Zhou J, Wong AH, Wang H, et al. 329 Early blood cell count test (BCT) for survival prediction for non-small cell lung cancer patients treated with atezolizumab: integrated analysis of 4 multicenter clinical trials. Journal for ImmunoTherapy of Cancer 2021;9: doi: 10.1136/jitc-2021-SITC2021.329 | Roche | N/A | |
| 5945 | Neeraj Narula | Hamilton Health Sciences | Predictors of Mucosal Healing in Ulcerative Colitis: A Post-hoc Analysis of VARSITY | Narula, N., Wong, E., Colombel, J. F., Riddell, R., Marshall, J., Reinisch, W., & Dulai, P. (2021). DOP03 Early change in epithelial neutrophilic infiltrate predicts long-term response to biologics in Ulcerative Colitis. Journal of Crohn’s and Colitis, 15(Supplement_1), S042–S043. doi: 10.1093/ecco-jcc/jjab073.042 | Takeda | N/A | N/A |
| 5945 | Neeraj Narula | Hamilton Health Sciences | Predictors of Mucosal Healing in Ulcerative Colitis: A Post-hoc Analysis of VARSITY | Narula, N., Wong, E. C., Colombel, J. F., Riddell, R., Marshall, J. K., Reinisch, W., & Dulai, P. S. (2021). Early Change in Epithelial Neutrophilic Infiltrate Predicts Long-Term Response to Biologics in Ulcerative Colitis. Clinical Gastroenterology and Hepatology. Published. doi: 10.1016/j.cgh.2021.07.005 | Takeda | 15 | |
| 5951, 4543 | Mathilde Nijkeuter | University Medical Center Utrecht | Individualized prediction of recurrence risk reduction and risk of bleeding with extended anticoagulation in patients with venous thromboembolism | de Winter MA, Dorresteijn JAN, Carrier M, Cohen AT, Hansen J-, Kaasjager HAH, Middeldorp S, Raskob GE,Sørensen HT, Visseren FLJ, Wells PS, Büller HR, Nijkeuter M. Individual Benefits and Harms of Extended Anticoagulation in Patients with Venous Thromboembolism: The VTE-PREDICT Model [abstract]. Res PractThromb Haemost. 2021; 5 (Suppl 1). https://abstracts.isth.org/abstract/individual-benefi ts-and-harms-of-extended-anticoagulation-in-patients-with-venous-thromboembolism-the-vte-predict-model/. Accessed July 23, 2021. | Boehringer Ingelheim, Daiichi Sankyo | N/A | N/A |
| 5984 | David Baker | Queen Mary University of London | Exploring possibilities to improve the risk benefit balance through analysis of the ocrelizumab phase II extension study | David Baker, Amy MacDougall, Angray S Kang, Klaus Schmierer, Gavin Giovannoni, Ruth Dobson. Seroconversion following COVID-19 vaccination: Can we optimize protective response in CD20-treated individuals?. Clinical and Experimental Immunology, 2021; uxab015. doi: 10.1093/cei/uxab015 | Roche | 15 | |
| 6062 | Alexander Meisel | University Hospital of Zurich | Neutrophils, Neutrophil-to-Lymphocyte Ratio (NLR) and Neutropenia as Predictors of Treatment Efficacy of Atezolizumab Monotherapy and Atezolizumab-Chemotherapy-Combinations | Meisel, A., Mark, M., Haider, A., Holer, L., Hayoz, S., Gebhard, C., Bengs, S., Hochmair, M., Cappuzzo, F., Reck, M., von Moos, R., & Stenner-Liewen, F. (2021). 1279P The prognostic value of chemotherapy-induced neutropenia (CIN) in patients with advanced non-small cell lung cancer (NSCLC) in the era of chemoimmunotherapy (CIT). Annals of Oncology, 32, S996. doi: 10.1016/j.annonc.2021.08.1881. | Roche | N/A | N/A |
| 6064 | Neeraj Narula | Hamilton Health Sciences | Comparative Effectiveness of Vedolizumab vs. Infliximab in Ulcerative Colitis | Narula N, Wong ECL, Marshall JK, Colombel JF, Dulai PS, Reinisch W. Comparative Efficacy for Infliximab Vs Vedolizumab in Biologic Naive Ulcerative Colitis. Clin Gastroenterol Hepatol. 2021 Jul 28:S1542-3565(21)00820-X. PMID: 34329776. doi: 10.1016/j.cgh.2021.07.038 | Johnson & Johnson, Takeda | 13 | |
| 6489 | Line Uhrenholt | Aalborg University Hospital | Tapering strategies of biological and targeted synthetic disease-modifying antirheumatic drugs for patients with inflammatory arthritis: a systematic review of randomised controlled trials | Line Uhrenholt, Robin Christensen, Wilfred K H Dinesen, Caroline H Liboriussen, Stine S Andersen, Lene Dreyer, Annette Schlemmer, Ellen-Margrethe Hauge, Conni Skrubbeltrang, Peter C Taylor, Salome Kristensen. Risk of flare after tapering or withdrawal of biologic/targeted synthetic disease-modifying anti-rheumatic drugs in patients with rheumatoid arthritis or axial spondyloarthritis: a systematic review and meta-analysis. Rheumatology, 2021. doi: 10.1093/rheumatology/keab902 | AbbVie | 5 | |
| 6499, 5323, 5289 | Ashley Hopkins | Flinders University | Predictors of therapeutic and adverse effects of medicines used in the treatment of breast cancer | Prediction of severe neutropenia and diarrhoea in breast cancer patients treated with abemaciclib. Modi, Natansh D. et al. The Breast, Volume 58, 57 – 62. doi: 10.1016/j.breast.2021.04.003 | Lilly | 5 | |
| 6642 | Neeraj Narula | Hamilton Health Sciences | Modified Multiplier SES-CD (MM-SES-CD) on Predicting Endoscopic Remission in Crohn's Disease | Neeraj Narula, Emily C L Wong, Jean-Frederic Colombel, William J Sandborn, Marc Ferrante, John K Marshall, Walter Reinisch, Parambir S Dulai, Early Reduction in MM-SES-CD Score After Initiation of Biologic Therapy is Highly Specific for 1-year Endoscopic Remission in Moderate to Severe Crohn’s Disease, Journal of Crohn's and Colitis, Volume 16, Issue 4, April 2022, Pages 616–624. Doi:10.1093/ecco-jcc/jjab183 | AbbVie, Johnson & Johnson, Takeda | 2 | |
| 6686 | Neeraj Narula | Hamilton Health Sciences | Extended Validation of an Ulcerative Colitis Vedolizumab Decision Support Tool | Parambir S Dulai, MD, Emily C L Wong, BS, Walter Reinisch, MD, Jean-Frederic Colombel, MD, John K Marshall, MD, MSc, Neeraj Narula, MD, Decision Support Tool Identifies Ulcerative Colitis Patients Most Likely to Achieve Remission With Vedolizumab vs Adalimumab. Inflammatory Bowel Diseases, 2021; izab310, doi: 10.1093/ibd/izab310 | Takeda | 5 |
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