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Center for Global Research Data

Approved Research Proposals

The table provides details of approved research proposals that have signed Data Use Agreements.

Data Request IDLead InvestigatorInstitutionResearch Proposal Title
3244Vojtech HuserNational Library of Medicine/NIHIdentification of Research Common Data Elements in HIV/AIDS using data science methods
3246Dawn FarrellInstitute of Technology Tralee​

Cochrane Review: Interventions for fatigue in inflammatory bowel disease
3270Mirjana Stanic BenicUniversity Hospital Centre Rijeka​The impact of biological interventions on health‐related quality of life in adults with Crohn's disease
3287Robert AlexanderTakedaIdentification of biomarkers associated with specific sleep variables
3288Marc-Antoine SparfelTours Hospital MIDRA: influence of demographic and environmental factors on anti-tumor necrosis factor efficacy in rheumatoid arthritis a systematic review and meta-analysis of randomized controlled trials
3320John FrewRockefeller UniversityAnalysis of Outcome Measures in Hidradenitis Suppurativa
3328Klaus GottliebEli Lilly USAMapping of components of the complete blood count and comprehensive metabolic profile to disease-specific clinical and endoscopy endpoints in phase 2 and 3 clinical trials of ulcerative colitis and Crohn’s disease
3361Gustav NilsonneKarolinska InstitutetDistribution of interleukin -6 in human plasma implications for statistical modelling and meta-analysis
3369 Michael Ward
NIH Predicting Treatment Response to Tumor Necrosis Factor Inhibitors in Patients with Ankylosing Spondylitis
3762Lin WangJohns Hopkins HospitalThe relative efficacy and safety of apalutamide, enzalutamide, abiraterone, and darolutamide for nonmetastatic castration-resistant prostate cancer
3876Changyu ShenBeth Israel Deaconess Medical CenterRisk and Benefit Stratification of Treatment Effects in Patients with Atrial Fibrillation
4036Akira KimataUniversity of TsukubaOptimal interruption time of dabigatran per OS to Ablation (O-A time) in patients with atrial fibrillation Integrated analysis of 2 randomized controlled clinical trials
4037Karl PeaceGeorgia Southern UniversityAssessment of Matching Methods for Causal Analysis
4039Claire DaienCHU lapeyronie The most appropriate conventional DMARD to combine with tofacitinib in Rheumatoid Arthritis post hoc analysis of ORAL sync study
4043Janneke van der WoudeErasmus Medical Center Effect of treatment on lipid profiles in patients with inflammatory bowel disease a systematic review and meta-analysis
4047Miriam Oron
Skintelligence ltd.Test the prospects of expending the Skintelligence algorithm for predicting response to treatment with Alefacept and Ustekinumab in psoriatic patients affected with type I diabetes
4048, 4329Shomron Ben-HorinSun Yatsen 1st affiliated HospitalEfficacy of biologic drugs in short-duration versus long-duration inflammatory bowel disease
4113Lesley InkerTufts Medical CenterChronic Kidney Disease Epidemiology – Clinical Trials Consortium (CKD-EPI CT)
4115Amir MahabadiUniversity Hospital Essen, West German Heart and Vascular Center Impact of statin therapy on coronary artery calcification volume and density – A meta-analysis of randomized controlled trials
4116 Sharon StraussSt. Michael’s HospitalComparative safety and effectiveness of cognitive enhancers for Alzheimer's dementia a systematic review and individual patient data network meta-analysis
4117John FrewRockefeller UniversityPredictors of Treatment Response, Adverse Events, Changes in Anaemia status and Assessment of Lesion Count Variability in Hidradenitis Suppurativa
4118J. David SpenceWestern UniversityOn-Treatment analysis of the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) Trial
4121Frederikus KlokLeiden University Medical CenterPerformance of the AF-adapted VTE-BLEED score for predicting major bleeding in patients with atrial fibrillation a post-hoc analysis of the ENGAGE-AF TIMI-48 Study
4275Lisa StampUniversity of OtagoSerum urate as a biomarker in gout Protocol for individual patient data analysis for OMERACT 2020
4278Jennifer QuintImperial College London Withdrawing inhaled corticosteroid (ICS) treatment in people with COPD a real world study
4316Martin OkunFort HealthCareGeospatial and Seasonal Variation in Psoriasis Severity Analysis of Placebo Response Data from Phase 3 placebo-controlled trials in moderate-severe psoriasis
4319Maria Alice FranzoiJules Bordet Institut
Clinical implications of body mass index and weight in metastatic breast cancer patients receiving abemaciclib. A combined individual patient level data sub-analysis of MONARCH 2 and MONARCH 3 trials
4327Michael SzarekSUNY Downstate Medical CenterAnalysis of Total Events and Hospitalizations in the SPARCL Study
4330Laure GossecSorbonne UniversitéDomains of health important for Rheumatoid Arthritis patients can be assessed separately: Reliability and Responsiveness of the Rheumatoid Arthritis Impact of Disease Score - 7 items (RAID.7i)
4540Chris GaleUniversity of LeedsEfficacy and safety of edoxaban versus warfarin in patients with atrial fibrillation and frailty insights from the ENGAGE AF-TIMI 48 trial
4543Mathilde NijkeuterUMC UtrechtPrediction of individualized recurrence risk reduction and risk of bleeding with extended anticoagulation in patients with venous thromboembolism
4915Rachel TomkoMedical University of South CarolinaPredicting Individuals' Probability of Response to Smoking Cessation Pharmacotherapy
4919Hendrik Jan GuchelaarLeiden University Medical Center (LUMC)Effect of digoxin on survival outcome in metastatic renal cell carcinoma patients treated with tyrosine kinase inhibitors
4920Gustavo TureckiDouglas Mental Health University InstitutePredicting Treatment Efficacy in Individuals with Major Depression -- Deep Neural Networks for Physiological Patient Parameters
4921Tim BrümmendorfUniversity Hospital Aachen Entropy – based Biomarkers for individualized response on Bosutinib treatment in chronic phase CML
4922, 3274Diane van der WoudeLeiden University Medical Center​Effect of rheumatoid factor and anticitrullinated peptide antibody on the efficacy of biological disease-modifying antirheumatic drugs in patients with rheumatoid arthritis
4926Eva-Maria GamperMedical University InnsbruckComparison of the EORTC QLU-C10D with generic utility instruments and development of a comprehensive manual for its use
4949, 3190Vivek RudrapatnaUniversity of California San FranciscoEfficacy of Crohn’s Disease Treatment Stratified by Disease Phenotype
5073Philip RobinsonUniversity of QueenslandAssessment of treatment outcome using ASAS40 with etanercept in non-radiographic axSpA by baseline CRP - a re-analysis of trial data
5074Sebastian ZundlerUniversity Hospital ErlangenEvaluation of the relationship between vedolizumab peripheral blood serum level at week 6 and binary clinical outcomes at week 10/14 - a meta-analysis
5080Joel SkaistisBeaumont Health Benefit of Anticoagulation in Cryptogenic Stroke According to Biomarker Level
5098Christopher BaethgeUniversity of Cologne Medical School Dose-response relationships in antidepressant pharmacotherapy of depressive disorders with (S)SNRI: a systematic review and meta-analysis
5099Jorge HernandoVall d ́Hebron University Hospital Impact of gender on multikinase inhibitors (MKIs) toxicity in patients (pts) with advanced pancreatic and gastrointestinal neuroendocrine tumors (NETs)
5163Susan BatesColumbia University Medical CenterAssessing the tumor growth and decay rates in patients with pancreatic cancer treated with Gemcitabine/Abraxane: Comparing real world data with clinical trial data
5166Thomas MetkusJohns Hopkins University School of Medicine Severe sepsis in the cardiac intensive care unit: management strategies and outcomes
5208Ahmad AbuhelwaUniversity of South Australia Predictors of exposure, therapeutic and adverse effects of certolizumab pegol and baricitinib used in the treatment of rheumatoid arthritis
5276Yan LuoKyoto UniversityPredicting the Treatment Response of Certolizumab for Individual Patients with Rheumatoid Arthritis: An Individual Participant Data Meta-Analysis
5291Sarah NevittUniversity of LiverpoolAntiepileptic drug monotherapy for epilepsy: an updated Cochrane review and individual participant data network meta-analysis
5292Désirée van der HeijdeLeiden University Medical CenterMeasurement properties of the instruments used in the outcome assessment of axial spondyloarthritis
5325Daniel GoldenholzBeth Israel Deaconess Medical Center Retrospective analysis of placebo arm data in clinical epilepsy trials
5327Jose Antonio Pereira da SilvaUniversidade de CoimbraLong-term predictive value of patient global assessment regarding radiographic damage and physical function in patients with Rheumatoid Arthritis individual patient data meta-analysis
5330Laura BonnettUniversity of LiverpoolModelling seizure rates rather than time to an event within clinical trials of antiepileptic drugs