Lead Investigator: Hanna Suominen, The Australian National University
Title of Proposal Research: Develop Type 1 Diabetes Simulators/Models for Exercise in Type 1 Diabetes
Vivli Data Request: 9963
Funding Source: The proposed research is funded by the ANU as part of Prof Suominen, Prof Nolan, and Dr Hettiarachchi’s existing employment at the ANU.
Potential Conflicts of Interest: None
Summary of the Proposed Research:
Artificial Pancreas Systems (APS) use glucose measurements to calculate insulin administration requirements in Type 1 Diabetes (T1D). These systems have limited information regarding daily activities such as “exercise” and the unknown variation of glucose within/among individuals challenges its regulation. This affects the safety and quality of life of people with T1D. Integrating additional physiological signals to APSs, provides an opportunity to improve treatment. However, “simulators” are required to safely design APSs and current simulators have limited modelling capabilities associated with exercise. Therefore, this project aims to develop an open-source T1D simulator which is capable of simulating the effects of exercise. This will be very valuable for the development and benchmarking of novel insulin treatment strategies.
Requested Studies:
Type 1 Diabetes EXercise Initiative Pediatric Study (T1DexiP): The Effect of Exercise on Glycemic Control in Youth with Type 1 Diabetes
Data Contributor: Jaeb Center for Health Research Foundation, Inc.
Study ID: T1-DEXIP
Sponsor ID: T1-DEXIP
Type 1 Diabetes EXercise Initiative: The Effect of Exercise on Glycemic Control in Type 1 Diabetes Study
Data Contributor: Jaeb Center for Health Research Foundation, Inc.
Study ID: T1-DEXI
Sponsor ID: T1-DEXI