Lead Investigator: Tomas Koutny, University of West Bohemia
Title of Proposal Research: In-Silico modelling
Vivli Data Request: 8922
Funding Source: None
Potential Conflicts of Interest: Dr. Koutny reports: I am a consultan to Abbott Laboratories. In the past, I delivered invited lectures at international congress organized by the Charles University in Prague, where directly targeted diabetologist life-time education. Along the university-affiliated use, I also intend to use the data for a personal contribution that would help the projects such as the OpenAPS one. In the best case, the individual patient data would be transformed to in-silico model parameters, which would allow in-silico modelling of the anonymized patients and could be published.
Summary of the Proposed Research:
As I am focused on in-silico modelling, I wish to explore the importance of excerise on the in-silico models of glucose metabolism when modelling the patients. With an advanced modelling of physical activity/exercise, the in-silico models could be considerably improved as regards their degree of realism. This would be an important step in pre-clinical trials and personalized diabetes care.
Requested Studies:
Type 1 Diabetes EXercise Initiative: The Effect of Exercise on Glycemic Control in Type 1 Diabetes Study
Data Contributor: Jaeb Center for Health Research Foundation, Inc.
Study ID: T1-DEXI
Sponsor ID: T1-DEXI
Type 1 Diabetes EXercise Initiative Pediatric Study (T1DexiP): The Effect of Exercise on Glycemic Control in Youth with Type 1 Diabetes
Data Contributor: Jaeb Center for Health Research Foundation, Inc.
Study ID: T1-DEXIP
Sponsor ID: T1-DEXIP