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Center for Global Research Data

Reasons for Denial of Data Requests

A full list of Vivli members’ data sharing policies can be found on their member’s page.

 

Reason Data Request Denied: Out of Scope of Data Contributor’s Data Sharing Policy

Data contributorStudies Research ProposalRequest ID
Pfizer 3Efficacy of Crohn's Disease Treatment Stratified by Disease Phenotype3190
Pfizer3Predicting Antidepressant Response in Children and Adolescents with Depression3360
Takeda2Interventions for Fatigue in Inflammatory Bowel Disease 3246
Pfizer1Risk of small for gestational age (SGA) after malaria in pregnancy using the Intergrowth 21st birth weight chart compared to a local weight chart as reference: A meta-analysis of individual participant level data5949
Pfizer3A Systematic Review to Describe the Demographic Diversity of Dermatologic Clinical Trial Participants for Common Dermatologic Diseases5086
Eli Lilly1Interferon (IFN) signatures as predictive markers of sensitivity to CDK4/6i in breast cancer6026
Pfizer1Predictors of therapeutic and adverse effects of medicines used in the treatment of gastrointestinal cancers5290
Pfizer7Development of model to predict pain response in clinical trials of chronic pain conditions6520
Boehringer Ingelheim1Genetic Correlation between stroke recurrence in patients treated with dabigatran and dabigatran plasma levels6628
Pfizer1Analgesic medicines for adults with low back pain: a systematic review and network meta-analysis6689
AbbVie1Identification of gene co-expression networks regulated by Interleukin-12 in RNA-sequencing data comparing skin biopsies form Ustekinumab and Risankizumab treated psoriasis patients7134
Pfizer1A Bayesian Exact Platform Design for Multi-arm trials with Concurrent or Historical Controls COVID7228

Reason Data Request Denied: The Data Request required data that was not collected in the studies

Data contributorStudies Research Proposal
Boehringer Ingelheim7Patterns and predictors of toxicity with afatinib for treatment of patients with advanced EGFR mutant NSCLC
Biogen1Inferential reproducibility of therapeutic research: a registered report for a cross-sectional study of RCTs available on major data-sharing platforms
AstraZeneca6A systematic review of the steroid sparing effect of biologicals in severe asthma

Reason Data Request Denied: The Data Request's project aim is commercial or litigious and The Data Request is out of scope

Data ContributorStudiesResearch Proposal
Pfizer6Data grant application of completed neuropathic pain clinical trials using pregabalin (Lyrica®) to validate the Quantitative Data Surveillance System (QDSS)

Reason Data Request Denied: Data collected subject to legal, contractual or consent provisions that prevent further sharing of clinical data

Data contributorStudies Research Proposal
Daiichi-Sankyo1Exploring Tripartite Estimands approach – Reanalysis of actual clinical trials to estimate the treatment effect for Clinical Trials
GlaxoSmithKline4Developing a Generalizable Blockchain Architecture to Enhance Clinical Trial Recruitment and Achieve Persistent Monitoring

Reason Data Request Denied: The data contributor or sponsor doesn't have the legal authority to provide the data

Data ContributorStudiesResearch ProposalRequest ID
Boehringer Ingelheim1Tolerability of duloxetine in the elderly and in adults: a systematic review and individual patient data meta-analysis of randomized controlled trials versus placebo.4112
Pfizer2Meta-analysis of efficacy of cholinesterase inhibitors on individual neuropsychiatric symptoms in Alzheimer's disease, Parkinson's disease and dementia with Lewy bodies 5924

Reason Data Request Denied: The Data Request competes with the data contributor/sponsor's publication plan

Data ContributorStudiesResearch ProposalRequest ID
Boehringer Ingelheim1The Effectiveness of a Software in Pulmonary Fibrosis Staging and Severity Evaluation in Idiopathic Pulmonary Fibrosis (IPF) Patients6631
Daiichi Sankyo1Big data and meta-analytic approaches for better phenotyping in atrial fibrillation and heart failure6541

Reason Data Request Denied: The Data Request's project aim is commercial or litigious

Data ContributorStudiesResearch ProposalRequest ID
Pfizer4Enhancing inference from real-world data using externally-derived missing data models: a pilot study of Ulcerative Colitis4041

Reason Data Request Denied: The data requested cannot be shared due to ongoing regulatory activities

Data ContributorStudiesResearch ProposalRequest ID
AstraZeneca1Validation of a Machine Learning-based Model to Predict the Risk of Heart Failure among Patients with Diabetes Mellitus: the WATCH-DM Risk Score6522
AstraZeneca1Development and validation of a prediction model for the indication of inhaled corticosteroid (ICS) in patients with chronic obstructive pulmonary disease (COPD)6712
Pfizer1Determining the impact of Tafamidis on weight loss and cachexia development in Transthyretin amyloidosis (ATTR) patients based on the ATTR-ACT trial (Acute Venous Thrombosis: Thrombus Removal with Adjunctive Catheter-Directed Thrombolysis (ATTR-ACT)7286

Reason Data Request Denied: The Data Request did not meet the data contributor/sponsor policies for informed consent

Data ContributorStudiesResearch ProposalRequest ID
Bristol Myers Squibb2A survival extrapolation study of ipilimumab + dacarbazine (IPIflDTIC) versus placebo + dacarbazine (PBOflDTIC) in melanoma patients in NCT00324155 trial: using flexible parametric relative survival models6859

Reason Data Request Denied: The Data Request's research proposal lacks clear scientific merit

Data ContributorStudiesResearch ProposalRequest ID
Pfizer5Data-sharing and re-analysis for main studies assessed by the European Medicines Agency - a cross-sectional study on European Public Assessment Reports5853
Regeneron1Data-sharing and re-analysis for main studies assessed by the European Medicines Agency - a cross-sectional study on European Public Assessment Reports5853
Regeneron3Recruitment and treatment outcomes of racial subgroups in Phase III clinical trial data evaluating diabetic macular edema and retinal vein occlusion.6688

Reason for Denial of Studies in a Data Request

Data contributorStudies Reason of Non-ApprovalResearch ProposalRequest ID
Pfizer2The Data Requested is out of scope of data sharing policyIdentification of Research Common Data Elements in HIV/AIDS using data science methods 3244
Pfizer1The Data requested is unavailablePredicting Treatment Response to Tumor Necrosis Factor Inhibitors in Patients with Ankylosing Spondylitis 3369
Boehringer Ingelheim1Document not available in EnglishRisk and Benefit Stratification of Treatment Effects in Patients with Atrial Fibrillation 3876
Eli Lilly5The data contributor or sponsor doesn't have the legal authority to provide the dataTolerability of duloxetine in the elderly and in adults: a systematic review and individual patient data meta-analysis of randomized controlled trials versus placebo.4112
Boehringer Ingelheim2The data requested is not appropriate for the research proposal in the Data RequestPredictors of therapeutic and adverse effects of medicines used in the treatment of breast cancer5289
UCB1Data collected subject to legal, contractual or consent provisions that prevent further sharing of clinical dataAntiepileptic drug monotherapy for epilepsy: an updated Cochrane review and individual participant data network meta-analysis5291
AbbVie1There is a reasonable likelihood that a patient could be re-identifiedSharing of Progressive Supranuclear Palsy (PSP) data with the Rare Disease Cures Accelerator - Data and Analytics Platform for Analysis of Outcome Measures and Other Purposes5989
Roche1The Data Requested is out of scope of data sharing policyPredictors of therapeutic and adverse effects of medicines used in the treatment of breast cancer5289
Pfizer1The data requested is unavailableComparative efficacy and tolerability of new-generation antidepressants for major depressive disorder in children and adolescents: protocol of an individual patient data meta-analysis4324
Pfizer3The data requested is unavailableInferential reproducibility of therapeutic research: a registered report for a cross-sectional study of RCTs available on major data-sharing platforms6055
Boehringer Ingelheim1The data contributor or sponsor doesn't have the legal authority to provide the dataAssessing heterogeneity in relative treatment efficacy by age, sex and comorbidity.5483
GlaxoSmithKline1The data requested is unavailableTositumomab: statistical modeling of expanded access programs and conventional trials6477
AbbVie1There is a reasonable likelihood that a patient could be re-identified (due to the very small number of patients)Exploring the heterogeneity of cognitive profile in patients with Progressive Supranuclear Palsy (PSP) enrolled in the ABBV-8E12 trial and the relationship to brain volumes7147